Ypsilanti, Michigan, features a pedestrian-friendly environment, particularly in its historic districts like Downtown, Depot Town, and West Cross. These areas offer a well-maintained network of sidewalks, making it easy to explore local shops, restaurants, and attractions on foot. The compact layout of these neighborhoods supports accessibility, though walking may be less convenient in areas further from the city center. Seasonal weather, such as snowy winters, could impact comfort, but overall, walking is a practical way to navigate key parts of Ypsilanti.

Biciklizam u Ypsilantiju podupire mješavina namjenskih biciklističkih staza i asfaltiranih staza koje povezuju različite dijelove grada. Područje obuhvaća infrastrukturu koja podržava vožnju biciklom, što ga čini praktičnom opcijom za kretanje, posebice na kraćim udaljenostima. Međutim, jednostavnost vožnje biciklom može ovisiti o određenim rutama i odredištima jer nisu sve ceste opremljene značajkama prilagođenima biciklima. Relativno ravan teren u mnogim područjima može vožnju biciklom učiniti pristupačnijom, no korisnici bi prilikom planiranja vožnji trebali uzeti u obzir vremenske uvjete i sigurnost na cesti.

Public transit in Ypsilanti is primarily served by a local bus system that connects key areas within the city and nearby regions. The Ypsilanti Transit Center acts as a central hub, making it relatively straightforward to access various destinations. Buses provide a practical option for getting around, especially for those traveling to nearby Ann Arbor or other local points of interest. However, factors such as seasonal weather conditions, including snow in winter, may occasionally impact transit schedules or travel comfort. Overall, public transportation offers a functional way to navigate the area for those without personal vehicles.