聖塔安娜有不少適合步行的地區，特別是市中心，當地設有便利的行人設施和緊湊的規劃，方便大家步行前往商店、餐廳和文化景點。不過，全市的步行便利程度各有不同，有些社區因距離較遠或行人設施有限而較難步行前往。當地天氣一般溫和宜人，適合大部分時間步行出行。雖然步行是探索聖塔安娜部分地區的方便方式，但對於較遠距離或連接較少的地區，未必是最實際的選擇。

Biking in Santa Ana comes with a mix of opportunities and challenges. The Santa Ana River Trail is a notable option, providing a dedicated path for cyclists away from traffic. However, bike lanes on city streets can be limited in some areas, and navigating busy roads may require caution. The relatively flat terrain makes biking manageable, but distances between destinations could vary. Weather conditions are generally favorable for biking, with mild temperatures and minimal rain.

Public transportation in Santa Ana provides accessible and convenient options for getting around the city. The Orange County Transportation Authority operates buses that connect key areas, and the Santa Ana Regional Transportation Intermodal Center serves as a hub for buses and trains, including Metrolink services. Public transit can be a practical choice for reaching many destinations, though the ease of use may depend on the distance and specific routes. The city’s infrastructure supports these options, but factors like walking distances to stops and the overall layout of the area may influence preferences.