Santa Ana ponuja kombinacijo območij, ki so primerna za pešačenje, zlasti v središču mesta, kjer pešcem prijazna infrastruktura in kompaktna zasnova omogočata enostaven dostop do trgovin, restavracij in kulturnih znamenitosti peš. Vendar pa se stopnja primernosti za pešačenje razlikuje po mestu, saj so nekatera naselja zaradi oddaljenosti ali omejene infrastrukture za pešce manj dostopna. Vreme je na splošno blago in prijetno, kar spodbuja hojo kot udobno možnost večji del leta. Čeprav je hoja lahko priročen način za raziskovanje določenih delov Santa Ane, ni vedno najbolj praktična izbira za daljše razdalje ali območja z manjšo povezanostjo.

Biking in Santa Ana comes with a mix of opportunities and challenges. The Santa Ana River Trail is a notable option, providing a dedicated path for cyclists away from traffic. However, bike lanes on city streets can be limited in some areas, and navigating busy roads may require caution. The relatively flat terrain makes biking manageable, but distances between destinations could vary. Weather conditions are generally favorable for biking, with mild temperatures and minimal rain.

Public transportation in Santa Ana provides accessible and convenient options for getting around the city. The Orange County Transportation Authority operates buses that connect key areas, and the Santa Ana Regional Transportation Intermodal Center serves as a hub for buses and trains, including Metrolink services. Public transit can be a practical choice for reaching many destinations, though the ease of use may depend on the distance and specific routes. The city’s infrastructure supports these options, but factors like walking distances to stops and the overall layout of the area may influence preferences.