Walking can be a practical way to navigate certain parts of Lewiston, Maine, particularly in its downtown area and compact neighborhoods. The city has pedestrian infrastructure in place, including sidewalks and crosswalks, which support accessibility. However, the feasibility of walking may depend on the distance between destinations, as some areas are more spread out. Seasonal weather, such as snowy winters, can also impact walking conditions. Overall, walking is a reasonable option for shorter trips or exploring central areas, but other transportation methods may be necessary for longer distances or during inclement weather.

Biking can also be a practical way to get around Lewiston, particularly for shorter distances. The city has some infrastructure in place to support cyclists, including bike lanes and trails, which can make navigating certain areas more accessible. However, the ease of biking may vary depending on the specific route, as some areas may lack dedicated bike paths. The terrain in Lewiston is generally manageable for most riders, but weather conditions and seasonal changes could impact biking comfort and safety.

El transporte público es atendido principalmente por un sistema de autobuses conocido como citylink, que conecta áreas clave dentro de Lewiston y la vecina ciudad de Auburn. Este servicio ofrece una manera práctica de acceder a muchos destinos, incluidos el centro de la ciudad y las áreas residenciales. Los autobuses están diseñados para adaptarse a los transbordos entre rutas, lo que facilita la navegación por la ciudad. Sin embargo, la efectividad del transporte público puede depender de destinos y horarios específicos. La infraestructura de la región es compatible con este modo de viaje, pero factores como la distancia y las condiciones climáticas pueden afectar su conveniencia para el uso diario.