Walking can be a practical way to navigate certain parts of Lewiston, Maine, particularly in its downtown area and compact neighborhoods. The city has pedestrian infrastructure in place, including sidewalks and crosswalks, which support accessibility. However, the feasibility of walking may depend on the distance between destinations, as some areas are more spread out. Seasonal weather, such as snowy winters, can also impact walking conditions. Overall, walking is a reasonable option for shorter trips or exploring central areas, but other transportation methods may be necessary for longer distances or during inclement weather.

Biking can also be a practical way to get around Lewiston, particularly for shorter distances. The city has some infrastructure in place to support cyclists, including bike lanes and trails, which can make navigating certain areas more accessible. However, the ease of biking may vary depending on the specific route, as some areas may lack dedicated bike paths. The terrain in Lewiston is generally manageable for most riders, but weather conditions and seasonal changes could impact biking comfort and safety.

Javni prijevoz uglavnom se sastoji od autobusnog sustava poznatog kao citylink, koji povezuje ključna područja unutar Lewistona i susjednog Auburna. Ova usluga nudi praktičan način za dolazak do mnogih odredišta, uključujući centar grada i stambene četvrti. Autobusi su dizajnirani tako da omogućuju presjedanja između linija, što olakšava kretanje gradom. Ipak, učinkovitost javnog prijevoza može ovisiti o određenim odredištima i voznim redovima. Infrastruktura regije podržava ovaj način putovanja, ali čimbenici poput udaljenosti i vremenskih uvjeta mogu utjecati na njegovu praktičnost za svakodnevnu upotrebu.