Walking in Guatemala City can be challenging due to its sprawling layout, limited pedestrian infrastructure, and safety concerns in certain areas. While some neighborhoods may be accessible on foot, distances between key destinations are often significant, making walking less practical for getting around the city as a whole. Additionally, uneven sidewalks and heavy traffic can pose obstacles. The weather, typically warm and humid, may also impact comfort during extended walks. For short distances within specific areas, walking can be an option, but it is advisable to plan routes carefully and remain aware of your surroundings.

危地馬拉城的腳踏車專用基礎設施有限, 且交通繁忙, 因此騎腳踏車出行十分困難。城市的佈局和交通壅塞情況, 可能會影響騎乘腳踏車導航的便利性, 尤其是在市中心地區。此外, 城市部分地區的丘陵地勢可能對腳踏車騎士造成困難。雖然騎乘腳踏車可能是短程或娛樂的一種選擇, 但在規劃使用腳踏車交通時, 務必要考慮安全以及缺乏適合腳踏車的廣泛道路。

瓜地馬拉市的公共運輸系統包括 Transmetro，這是一種設有專用車道的快捷公車系統，有助於減少主要路線的壅塞。此外，傳統的「雞公車」也廣泛運行，連接市區及鄰近地區。雖然這些選擇價格實惠且使用普遍，但基礎設施有時可能導致延誤，特別是在尖峰時段。城市的丘陵地形和交通狀況也可能影響行車時間。大眾運輸通常是市區內移動的實用方式，但若需前往較遠或鄉村地區，則可能需要其他交通方式。