Sanford offers a walkable downtown area with pedestrian-friendly streets, making it convenient to explore local shops, restaurants, and attractions on foot. The city has invested in infrastructure like sidewalks and crosswalks, particularly in its historic district and along the scenic waterfront. However, outside the downtown core, destinations may be more spread out, and walking could become less practical. Additionally, the warm and humid climate, especially during summer, might make walking less comfortable for extended periods. For shorter distances and leisurely exploration, walking can be an enjoyable option in certain parts of Sanford.

桑福德提供適合單車的基礎設施, 包括徑和單車徑, 是一個合理的出行選擇。值得一提的是, 塞米諾爾韋基瓦步道為騎單車者提供了一條安全、風景優美的路線。大部分地區均可騎單車前往, 但距離和交通路線會視乎目的地而有所不同。該地區地勢平緩, 適合舒適的單車體驗, 但乘客亦應考慮天氣狀況, 例如酷熱或下雨, 可能會影響舒適度和安全性。

桑福德的公共交通選擇包括當地巴士服務, 以及前往地區鐵路系統的交通服務。免費電車服務接駁市中心和主要地點, 方便你探索桑福德市中心。該市亦受益於在塞米諾爾縣各地營運的即叫即到的微型交通服務, 提供靈活的行程選擇。雖然公共交通工具是在該地區穿梭的方便方式, 但目的地之間的距離和路線可用性等因素可能會影響部分行程的實用性。