Walking in Santa Maria, California, can be a practical option in certain areas, particularly for short distances or within neighborhoods. The city features some pedestrian-friendly infrastructure, including sidewalks and crosswalks, but its layout and suburban character often mean that destinations may be spread out, making longer walks less convenient. The weather is generally mild, which is favorable for walking, though the lack of extensive shaded areas in some parts may be a consideration during warmer days. While walking is feasible for accessing parks or local amenities, other transportation methods may be more efficient for covering greater distances.

Sykling i Santa Maria støttes av infrastruktur, blant annet sykkelfelt og veier, som gjør det enkelt å komme seg rundt med sykkel i enkelte områder. Byens relativt flate terreng er gunstig for sykling, og avstanden mellom viktige steder er ofte rimelig for syklister. Tilgjengeligheten og tilkoblingsmulighetene til sykkelfelt kan imidlertid variere, så det er nyttig å planlegge ruter på forhånd. Det milde været sørger for komfortable sykkelforhold hele året.

Public transportation in Santa Maria is provided through a bus system operated by Santa Maria Regional Transit. The network includes local and regional routes, making it possible to travel within the city and to nearby areas. Buses connect key destinations, but the spread-out nature of the city may require planning for longer trips. The infrastructure supports accessibility, and affordable fares make it a practical option for many. However, the convenience of public transit may depend on the proximity of bus stops to your destination and the frequency of service.