Walking is an excellent way to explore Key West, as the island is compact and many attractions are within a short distance of each other. The flat terrain and pedestrian-friendly infrastructure, including sidewalks and crosswalks, make navigating on foot convenient. The tropical climate, however, can be hot and humid, especially during midday, so staying hydrated and wearing sun protection is essential. While most popular spots are easily accessible by walking, the heat or occasional rain showers might make walking less comfortable at times.

騎腳踏車是探索基韋斯特的另一種實用方式, 這裡有適合腳踏車的基礎設施, 包括遍布該地區的腳踏車專用道和腳踏車架。由於景點間距離較短, 許多熱門目的地皆可騎腳踏車前往。地勢平坦, 騎乘很舒適, 但天氣炎熱時, 可能需要補水和防曬。

Public transit is a convenient option for navigating Key West, with bus routes like the Duval Loop providing easy access to popular areas such as Old Town and the historic district. The Lower Keys Shuttle connects Key West to nearby areas, making it a practical choice for exploring beyond the island. The compact size of Key West means many destinations are close together, and public transit is well-suited for short distances. However, the tropical climate may make waiting for buses less comfortable during hot or rainy conditions.

在基韋斯特，渡輪主要用於觀光行程，而非當地交通。例如，渡輪可連接基韋斯特與乾龜國家公園，每天都有適合行人及可攜帶自行車的航班。這些行程單程通常約需 2 小時。不過，渡輪並非基韋斯特本島的主要交通方式，因為該島面積不大，其他方式即可輕鬆移動。天氣與海象有時會影響渡輪時刻表，因此不太適合作為日常通勤的固定選擇。