Å gå til fots kan være en praktisk måte å komme seg rundt i enkelte områder av Pueblo, Colorado, spesielt i sentrum hvor reisemålene ligger tettere. Byen har gjort tiltak for å forbedre mulighetene for å gå, blant annet gjennom utbygging av fortau og turstier. Hvor godt det lar seg gjøre å gå, avhenger imidlertid av det aktuelle området, siden noen nabolag er mer spredt. Pueblos generelt milde klima gjør det mulig å gå store deler av året, men varme sommere kan kreve ekstra forholdsregler. Selv om det er praktisk å gå korte avstander, kan byens utforming og infrastruktur gjøre at andre transportmidler er mer hensiktsmessige for lengre turer.

Pueblo offers a growing network of bike paths and shared-use trails, making biking a practical way to get around certain areas of the city. Many routes are designed to connect neighborhoods and key destinations, providing safer and more accessible options for cyclists. However, some areas may still lack extensive biking infrastructure, which could affect convenience. The city’s relatively flat terrain is favorable for biking, though longer distances between destinations might require additional planning. Weather conditions, such as wind or heat, can also influence biking comfort, so riders should prepare accordingly.

Public transit in Pueblo is primarily served by a local bus system that connects various parts of the city. The bus routes provide access to key destinations, including schools, shopping areas, and community hubs. While the system is functional for many local trips, the spread-out nature of the city and its surrounding areas may make it less convenient for reaching more remote locations. The infrastructure supports basic transit needs, but factors like distance and limited route coverage could influence whether public transportation is the most practical option for getting around.