Grâce à sa forme compacte et à ses rues piétonnières, la marche est un moyen pratique d'explorer Guanajumato. Les allées étroites et virages plats de la ville se prêtent mieux à pied et vous permettent d'accéder facilement à de nombreuses attractions. Cependant, dans certaines régions, le terrain accidenté et les nombreux escaliers peuvent rendre la marche physiquement exigeante. Il est recommandé d'avoir des chaussures confortables, et les personnes à mobilité réduite peuvent trouver certains itinéraires difficiles. Le temps frais en milieu de journée est généralement agréable, mais il est préférable d'éviter la chaleur du midi pendant les mois les plus chauds.

Biking in Guanajuato can be challenging due to its steep hills, narrow streets, and cobblestone roads, particularly in the historic centre. The city’s topography makes it less practical for daily commuting by bicycle, especially for those unfamiliar with the area. While some areas may be accessible by bike, the lack of extensive bike-friendly infrastructure and the uneven terrain can make biking less convenient. For those considering biking, it is important to plan routes carefully and be prepared for the physical demands of navigating the city’s unique landscape.

Public transportation in Guanajuato is a convenient way to navigate the city’s compact layout and narrow streets. Local buses are a common option, connecting various parts of the city, including the bus station to the city center. The city’s unique topography, with its steep hills and tunnels, can make walking challenging, so public transit is often a more convenient choice. However, the narrow streets and hilly terrain may occasionally affect bus routes and schedules. Public transit is generally accessible for reaching key areas, making it a reasonable option for getting around.