Carbondale offers a walkable environment in certain areas, particularly near the downtown and university districts, where destinations are relatively close together. Sidewalks and pedestrian-friendly infrastructure are present in many parts of the city, making walking a practical option for short trips. However, the feasibility of walking may vary depending on the distance between destinations and the weather, as the region experiences hot summers and cold winters. For those staying within compact areas, walking can be a convenient and pleasant way to explore, but longer distances may require alternative transportation.

In addition to walking, Carbondale features a growing network of bike routes, making it a practical option for getting around the city. The infrastructure includes designated bike paths that connect various parts of the city, including Southern Illinois University. The relatively compact layout of Carbondale makes many destinations accessible by bike. However, factors like road conditions and distances to outlying areas may influence the ease of biking.

For those seeking alternatives to driving, public transit in Carbondale, Illinois, is a practical option for getting around the city and nearby areas. The Saluki Express provides reliable bus service for students, residents, and visitors, connecting key locations such as Southern Illinois University and other community destinations. Additionally, regional transit services like Rides Mass Transit District and JAX Mass Transit offer fixed-route and door-to-door options, making it easier to travel within the city and surrounding counties. The availability of these services helps navigate Carbondale efficiently, though factors like distance and scheduling should be considered when planning trips.