Walking in Calama can be a practical option in certain areas, as the city is relatively compact in its central zones. However, the arid desert climate, characterized by high temperatures and minimal shade, may make walking less comfortable during the day. Additionally, distances between key points of interest or residential areas and commercial zones may vary, potentially requiring alternative transportation for longer trips. While pedestrian infrastructure exists, it is advisable to plan routes carefully and consider the weather conditions before setting out on foot.

Cycling in Calama offers a mix of opportunities and challenges, with the city featuring both paved and unpaved roads. However, the arid desert climate and high altitude may pose challenges for some riders, particularly over longer distances. While some areas may be accessible by bike, the lack of extensive dedicated cycling infrastructure could make navigating certain parts of the city less convenient. Riders should also consider the condition of roads and plan routes carefully to ensure a smoother experience.

Buses form the backbone of public transportation in Calama, connecting various parts of the city and nearby areas. The infrastructure supports intercity travel, making it possible to reach destinations like Antofagasta or San Pedro de Atacama by bus. Within the city, buses can be a practical way to get around, though the arid climate and distances between some locations may influence convenience.