Walking in Rosario, Santa Fe, is a practical way to explore many parts of the city, thanks to its pedestrian-friendly infrastructure. The city features tree-lined streets, numerous parks, and well-maintained sidewalks, making it comfortable for walking. Many neighborhoods are easily accessible on foot, with traffic lights and crosswalks supporting pedestrian safety. However, the feasibility of walking may depend on the distance between destinations, as some areas are more spread out. The generally mild climate is conducive to walking, though summer heat might make longer walks less appealing during peak hours.

Cycling in Rosario is supported by a growing network of bike-friendly infrastructure, including dedicated bike lanes and paths that make it a practical way to navigate the city. The relatively flat terrain of Rosario supports easy biking, and many key areas are accessible by bicycle. However, factors such as traffic conditions and the availability of bike parking may influence the experience. Biking can be an efficient and eco-friendly option for short to moderate distances, especially in areas with established cycling routes.

Public transit in Rosario is centered around an extensive bus network with 63 lines connecting various parts of the city. This system provides access to many urban destinations, making it a practical option for getting around. The city also features a trolleybus system, adding to the available transit choices. Dedicated lanes for public transportation improve efficiency in some areas. However, the ease of travel may depend on the distance and specific routes. The infrastructure supports reliable transit, but weather conditions could occasionally impact comfort or accessibility.