Walking can be a practical way to navigate certain parts of Lewiston, Maine, particularly in its downtown area and compact neighborhoods. The city has pedestrian infrastructure in place, including sidewalks and crosswalks, which support accessibility. However, the feasibility of walking may depend on the distance between destinations, as some areas are more spread out. Seasonal weather, such as snowy winters, can also impact walking conditions. Overall, walking is a reasonable option for shorter trips or exploring central areas, but other transportation methods may be necessary for longer distances or during inclement weather.

Biking can also be a practical way to get around Lewiston, particularly for shorter distances. The city has some infrastructure in place to support cyclists, including bike lanes and trails, which can make navigating certain areas more accessible. However, the ease of biking may vary depending on the specific route, as some areas may lack dedicated bike paths. The terrain in Lewiston is generally manageable for most riders, but weather conditions and seasonal changes could impact biking comfort and safety.

Veřejná doprava je primárně obsluhována autobusovým systémem Citylink, který spojuje klíčové oblasti Lewistonu a sousedního Auburnu. Tahle služba nabízí praktický způsob dopravy do mnoha destinací, včetně centra města a obytných oblastí. Autobusy jsou navrženy tak, aby vyhovovaly přestupům mezi trasami a usnadňovaly navigaci po městě. Efektivita veřejné dopravy ale může záviset na konkrétních cílech a jízdních řádech. Infrastruktura v regionu tenhle způsob cestování podporuje, ale na vhodnost jízdy můžou mít vliv vzdálenosti nebo povětrnostní podmínky.