Buffalo offers a moderately walkable environment, with several neighborhoods providing pedestrian-friendly infrastructure. The city has made efforts to enhance walkability, particularly in areas like downtown, where sidewalks are well-maintained and crosswalks are accessible. However, the weather can be a factor, as harsh winters may deter walking during colder months. Distances between attractions can vary, making walking more suitable for exploring specific districts rather than traversing the entire city. Overall, walking is a practical option for short distances and enjoying the local scenery in certain parts of Buffalo.

Buffalo offers a growing network of bike-friendly infrastructure, making biking a practical way to get around. The city has dedicated bike lanes and trails that connect various neighborhoods, enhancing accessibility for cyclists. While the terrain is generally flat, which is favorable for biking, weather conditions can vary, potentially affecting ride comfort. The city continues to develop its biking infrastructure, aiming to improve safety and connectivity for cyclists.

The city features a range of public transportation options that make getting around the city convenient. The Metro Bus and Rail system provides extensive coverage, with buses and a light rail line connecting key areas such as downtown, universities, and residential neighborhoods. The light rail runs above ground in the city center and underground in other areas, making it a reliable choice regardless of weather conditions. Buses are frequent and cover a wide network, ensuring accessibility to various destinations. The infrastructure supports easy transfers between bus and rail, making public transit a practical option for navigating Buffalo.