Walking is a convenient way to explore La Crosse, particularly in its downtown area, which is known for being pedestrian-friendly. The city offers well-maintained sidewalks, crosswalks, and accessible pathways, making it easy to navigate on foot. Additionally, the compact layout of downtown ensures that many restaurants, shops, and attractions are within a short walking distance. However, the feasibility of walking may vary depending on the season, as winters can bring snow and icy conditions that might impact comfort and safety. Overall, walking is a practical option for shorter distances and central locations.

騎單車亦是另一種實用的出行方式，多得 La Crosse 已設有完善的單車徑、步道及其他配套設施，方便單車使用者。市內不少地區都可騎單車到達，無論通勤或探索都十分方便。La Crosse 的城市規劃相對緊湊，進一步提升了對單車友善的程度，不過騎士亦要留意本區地勢較多山，有些路段可能需要額外體力。當地的單車共享計劃 Drift Cycle，為需要短途或日常租用單車的人士提供了更多選擇。

Public transit in La Crosse is primarily served by the Municipal Transit Utility (MTU), which operates a network of fixed-route buses. The system is designed to connect key areas, including colleges and other central destinations, making it a practical option for getting around. The compact layout of La Crosse helps make bus travel accessible, with stops clearly marked by blue and white signs. However, the city’s long and narrow geography may require some planning to navigate efficiently. Public transit can be a convenient choice, especially for those traveling within the main service areas.