Walking in Saint-Louis can be a convenient way to explore the area, particularly for short distances. The town features a compact layout with accessible streets and pedestrian-friendly zones, making it easy to navigate on foot. Many essential amenities, such as shops and local markets, are within walking distance in central areas. However, the weather, typical of northeastern France, may vary seasonally, with colder winters potentially making walking less appealing. For longer distances or connections to nearby cities, other transportation options may be more practical.

Cycling in Saint-Louis offers a network that connects well with nearby areas, including cross-border routes to Switzerland. The city features bike paths and greenways that make many destinations accessible by bicycle. The relatively compact layout and cycling-friendly infrastructure support biking as a practical option for getting around. Additionally, regional trains in the area often allow bicycles, which can extend travel possibilities. However, factors such as terrain or specific distances may influence the ease of cycling depending on the destination.

Public transportation in Saint-Louis offers convenient options for navigating the area and nearby regions. The city is well-connected by buses and trains, with regular services linking Saint-Louis to neighboring cities, including Basel in Switzerland. Public buses provide access to local destinations, while trains offer efficient travel for longer distances. The infrastructure supports smooth transit, and the proximity of key locations makes public transport a practical choice for getting around.