Denham offers a pleasant environment for walking, with its charming village atmosphere and access to scenic routes. Many amenities and attractions are within a reasonable distance, making it convenient to explore on foot. The area features pedestrian-friendly paths, and its natural surroundings, including parks and green spaces, provide enjoyable walking experiences. However, the feasibility of walking may depend on individual preferences and the specific destinations, as some areas might require longer distances. Overall, walking is a practical option for getting around and enjoying the local charm of Denham.

Cycling in Denham is another enjoyable way to explore the area, especially with its proximity to scenic routes like those in the Colne Valley. Some national cycle routes pass through or near Denham, offering access to picturesque landscapes. However, the availability of dedicated cycling infrastructure may be limited, and cyclists may need to share roads with vehicles in certain areas. The relatively compact size of the region makes shorter trips manageable by bike, though care should be taken on busier roads.

Public transportation in Denham offers convenient options for both visitors and residents. The area is served by a train station, providing connections to nearby towns and cities, and there are bus routes within a short distance, including services to Uxbridge. The infrastructure supports accessibility with features like step-free access at the train station. Public transit can be a practical choice for navigating the region, especially for those traveling to nearby urban areas, though the rural setting may require some planning for less frequent services.